As if we don’t already have enough reasons to keep our cholesterol in a healthy range now there is a new study that suggests high cholesterol levels could boost the risk of Alzheimer’s disease by creating more brain clogging bits known as plaque. This finding doesn’t directly prove that high cholesterol causes Alzheimer’s, or that by lowering you would reduce the risk. Additionally, researchers failed to find a correlation between high cholesterol and tangles, which have been proven to clog the brain in those with Alzheimer’s. Nevertheless, the findings add to previous research that has linked insulin resistance to Alzheimer’s patients, said study author Dr. Kensuke Sasaki. Better control of both cholesterol levels and insulin resistance, both risk factors for heart disease, “might contribute to a strategy for the prevention of Alzheimer’s disease,” said Sasaki, an assistant professor of neuropathy at Kyushu University in Japan. The Alzheimer’s Association estimate there are 5.4 million Americans with the disease and expects the numbers to swell to a staggering 16 million by the year 2050 due to an aging population. Currently Alzheimer’s disease holds the distinction of being one of the few diseases for which there is no cure and no sure fire way to prevent its onset though some studies suggest that omega 3 rich supplements such as fish oil may at least deter the development of the disease. The researchers studied the brains of 147 individuals. This test group was comprised of 76 men and 71 women who were residents of a Japanese town and alive in 1988 when they underwent clinical examinations. They all were autopsied between 1998 and 2003. Thirty-three percent of them were diagnosed with dementia during life, although they didn’t show signs of it in 1988. Compared to people with low cholesterol levels, those with high cholesterol were more likely to have bits of protein in the brain known as plaques: 62 percent versus 86 percent. On the other hand brain tangles, which are bits of another kind of protein, showed no correlation to high cholesterol levels. One noted neurologist said the research is credible and intriguing adding to existing speculation that higher cholesterol levels in midlife, particularly LDL/bad cholesterol, increases the risk of Alzheimer’s later in life. He went on to say that it is unclear exactly how cholesterol may make plaques more common but suspects that a predisposition of some kind combined with high cholesterol levels could trigger a series of internal responses leading to its development. |
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evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
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Cholesterol Health
