Liver Disease in Pets
      
    I admit when I go to a party and say, “Pass the pâté de foie gras, please,”
    that I’m not really interested in the actual liver hors d'oeuvres, but I just
    like to say, “pâté de foie gras.” The words roll over my tongue like
    expensive chocolate on a hot date.  However, when my French Poodle,
    Mimi, developed jaundice, it brought a whole new meaning to foie gras. I knew Mimi
    was jaundiced because her normally pink gums and ears had become a golden yellow,
    and not even Mimi’s fuchsia sweater brought out her normally healthy glow. Jaundice
    is a result of too much bilirubin in the bloodsteam. When the liver is healthy, it removes
    the bilirubin from the bloodstream keeping it from accumulating to dangerous levels.

    The liver detoxifies contaminates in our blood by reducing them into a form we can
    eliminate, in other words—it breaks them down. The liver also synthesizes hormones,
    enzymes and proteins. And because the liver is important for digestion, Mimi had lost
    weight. My veterinarian, Dr. McKenna, said that Mimi was actually fortunate, because
    many animals with liver problems suffer from vomiting, diarrhea, poor appetite, and
    black mucus.  Liquid will even pool in their abdomen and they will look bloated, because
    as the liver fails, it stops making blood proteins and the blood becomes so thin fluid leaks
    out of the vascular system into the abdomen. Abnormal bruising can often be seen.

    I rushed Mimi in to Dr. McKenna as soon as I noticed something was wrong. Mimi loves
    Dr. McKenna. I think it might be because his clothes are…well…interesting. Not only
    does he wear the most bizarre colors, but he is also a rather rotund man who usually
    has at least a splash of gravy on his shirt. Mimi tried her best to give the polyester a
    lick, but even smell of country-fried steak didn’t excite her that day.

    “Has she been drinking a lot?” Dr. McKenna asked.

    “You know I don’t allow my pets to have alcohol!” I said.

    “Water,” he retorted. “Is she drinking a lot of water?”

    “Oh, come to think of it, she has been emptying her water before I get home
    from work.”

    “Let’s run some blood tests and do a bile acid assay, and see if we can nail this down.”

    Then he gave me a pamphlet about liver disease. It was much like one I’d read in my own
    physician’s office, but the illustrations were hairier.  It said liver disease could be caused
    from many different things. Just like people, Dogs can get liver disease from the hepatitis
    virus, which is called infectious canine hepatitis.  Bacteria called leptospirosis can also
    cause liver disease in animals. Many chemicals can lead to liver disease. Insecticides,
    phosphorus, anti-freeze, rat poison, selenium and iron can cause liver failure. Drugs or
    medications like anesthetic gases, antibiotics, antifungals, dewormers, steroids and
    analgesics like NSAIDS can cause liver disease also, but most drug reactions are from
    long-term use. Parasites like heartworms can cause liver disease. Even ingesting certain
    plants can lead to liver failure. Ragwort, certain mushrooms, blue-green algae and molds
    such as aflatoxin, which grows on corn, can be toxic.

    One kind of liver disease called Copper Storage Disease is a result of too much copper
    in the bloodstream. This type of liver disease is usually specific to certain breeds and
    genetic in origin. Bedlington Terriers, Doberman Pinschers, Skye Terriers, and West
    Highland White Terriers and Dalmatians are the most susceptible to this type of liver
    disease.

    Some kinds of liver conditions are rare. Portosystemic shunts are an abnormal vascular
    condition whereby blood is diverted past the liver without having the toxins removed.
    One type of this condition appears more commonly in purebreds and is considered
    genetic in origin. Portosystemic shunting to different vascular connections can affect
    varying breeds at different ages and is seen as a developmental disorder, or it can
    even be the result of a primary liver problem. Animals suffering from portosystemic
    shunts commonly have vomiting and diarrhea and will usually need surgery in order
    to survive.

    At the onset of liver disease, the liver cells swell and enlarge. As the disease progresses
    the cells die and are replaced by scar tissue. This rubbery condition is called cirrhosis.  
    It is important to treat liver disease in the early stages because cirrhosis is not
    reversible, even though 80% of liver cells must die before the liver fails.

    When Dr. McKenna returned, he seemed concerned, but not devastated. “I also did an
    ultrasound on Mimi. She may have a trauma related problem. Has she been hurt in any
    way?”

    “Well, she did go flying out of her car carrier a few days ago when I had to slam on the
    breaks, but she seemed okay. I guess I didn’t have the zipper completely closed.”

    “See this bruise?” Dr. McKenna showed me a dark spot on Mimi’s hind quarter.

    “Oh my gosh! My baby has a boo-boo. Could this be what’s wrong with her?”

    “It could be. Let’s take an x-ray and let me start her on some IV fluids. Why don’t we
    keep her overnight and I’ll call you and let you know if I find anything? Trauma to the
    liver can usually heal by itself.”

    “I feel like such a bad mother.”

    “Whatever it is, we are catching it pretty early according to the tests. There are some
    dietary changes you will probably need to make and a few other things I can prescribe.
    She is really healthy overall. There is a good chance she’ll be fine. Many kinds of liver
    disease can’t be treated. We just have to manage the symptoms.

    “What kind of prescriptions?” I asked in a desperate attempt to assuage the guilt
    creeping up on me.

    ”Ursodiol  is one. It replaces toxic bile acids with a type of bile that is less toxic.”

    “What about antibiotics or steroids?” I asked.

    “It depends on the cause of the liver problem. Sometimes steroids cause liver disease,
    so we have to be careful.”

    I kissed Mimi on the head and told her how much I loved her. I had a feeling she was
    going to be fine.

    Natural and complementary therapies to alleviate symptoms of liver disease

    These would include:

    *Herbal medicines (naturopathy)
    *Homeopathy
    *Acupuncture

    A combination of herbal and homeopathic remedies such as Silybum marianus, Arctium
    lappa, Chelidonium majus, Kali mur, Nat phos and Nat sulph can be used to promote
    a healthy liver.  

    Vitamin K and Vitamin E help some pets. There’s some natural remedies like Burdock
    and Greater Celandine that some of my clients use. Milk thistle is another.”

    Herbal and homeopathic remedies may also be used alongside conventional treatment
    for liver disease, but remember to discuss this with your veterinarian.

    Source: Article provided by purchaseremedies.com contributing expert author and
    researcher Sheli Ellsworth

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Liver disease in animals  
encompasses an entire
spectrum  of illnesses:

▪Hepatic Encephalopathy-
a brain disorder from
toxic  levels of ammonia  
entering the bloodstream.

▪Hepatic Lipidosis-a fatty  
liver disease treated  
usually treated
by dietary change.

▪Jaundice or Icterus-is
caused from an  
accumulation of
bilirubin or bile in
the blood.

▪Feline Infectious  
Peritonitis-coronal-like
viral infection that can be  
avoided with the FIP  
vaccine.

▪Cancer of the Liver-
is   uncommon in cats
and   dogs and may   
gravitate  from other
organs as well  as
spread to them.

▪Infectious Liver Disease  
(Hepatitis)- a viral form
of liver failure.

▪Parasitic Liver Disease-
is caused from parasites
like heartworms.

▪Arteriovenous Fistula-
rare disease usually  
congenital where  
abnormal passages  
develop between the  
hepatic liver arteries
and   the inner liver
portal veins.

▪Cirrhosis-death of liver
cells from many causes.

▪Enlarged Liver or  
hepatomegaly-caused  
from fatty infiltration to
the liver. More common
in cats.

▪Gall Bladder Problems-
the gallbladder stores
bile for the liver and can  
become blocked.
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